Effect of consumption of honey on glycemia in normal and hyperglycemic mice due to alloxane

Abstract

Diabetes Mellitus is a chronic pathology of metabolic origin, which appears due to the fact that the pancreas does not produce the amount of insulin that the human body needs, or of a lower quality. In this work we tried to define the effect of the consumption of honey on the glycemia in healthy and hyperglycemic male mice induced to diabetes by alloxane. For this, four groups of six male Swiss albino mice each were used. normoglycemic with regular diet treated with water; normoglycemic with diet + honey; hyperglycemic with regular diet treated with water and finally, hyperglycemic with alloxane with diet + honey. The treatment lasted for three days. The results indicated that the hypeglycemic animals that received honey for three days showed a favorable glycemic profile, since a significant decrease in sugar level was observed in this group after 2 and 4 hours of consumption of honey. The addition of honey in the group of hyperglycemic animals with a controlled diet contributes to achieving significantly lower glycaemia than in the group of hyperglycemic animals that do not receive honey.